James Shaw Grant, Highland Villages

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Three decades of basic cancer research have revealed that mutations in components of signalling pathways that control cell growth in primitive metazoans underlie tumour initiation in mammals. The Ras, PI(3)K and mTOR (mammalian target of rapamycin) signalling pathways form an intersecting biochemical network that, when mutated, drives cell growth in a manner unrestricted by environmental cues. ...

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ژورنال

عنوان ژورنال: Northern Scotland

سال: 1977

ISSN: 0306-5278,2042-2717

DOI: 10.3366/nor.1977.0008